One of my favorites (and Cassie's), Urban Brew Labs, closed on September 10th due to inadequate beer sales. They ran out of my favorite brew a couple of weeks earlier but I still managed to get there on the 9th to wish them luck.
In a bit of Karmic balancing, Smylie Brothers closed their awful Lakeview location (on my birthday of all things!), for no apparent reason. I mean, my hypothesis would have to include the food and beer, but owner Michael Smylie declined to comment when Block Club Chicago asked about it.
That still leaves almost 140 breweries and distilleries on the Brews & Choos Project list, including 63 I've yet to visit. And I plan to, with somewhat more vigor after I move next month.